Murakami keeps Japanese hopes alive at F.skating worlds

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Scientists reveal genetic mutation depicted in van Gogh's sunflower paintings

ScienceDaily (Mar. 29, 2012) ? In addition to being among his most vibrant and celebrated works, Vincent van Gogh's series of sunflower paintings also depict a mutation whose genetic basis has, until now, been a bit of a mystery.

In a study published March 29 in the journal PLoS Genetics, however, a team of University of Georgia scientists reveals the mutation behind the distinctive, thick bands of yellow "double flowers" that the post-Impressionist artist painted more than 100 years ago.

"In addition to being of interest from a historical perspective, this finding gives us insight into the molecular basis of an economically important trait," said senior author John Burke, professor of plant biology in the UGA Franklin College of Arts and Sciences. "You often see ornamental varieties similar to the ones van Gogh painted growing in people's gardens or used for cut flowers, and there is a major market for them."

The most common sunflower phenotype is a composite flower head that contains a single whorl of large, flattened, yellow ray florets on the outer perimeter and hundreds to over a thousand individual, tubular, disc florets that can produce seeds. The double-flowered mutants that van Gogh depicted in many of his paintings, on the other hand, have multiple bands of yellow florets and a much smaller proportion of internal disc florets.

To understand the genetic basis of this difference, Burke and his colleagues began by using the same plant crossing techniques that Gregor Mendel, a 19th century contemporary of van Gogh, used to lay the foundation of modern genetics. The scientists crossed the common, or wild type, variety of sunflower with the double-flowered variety. Their initial findings suggested that a single, dominant gene was responsible for creating the double-flowered mutation. Subsequent crosses of the offspring revealed that a second mutation, which is recessive to both the double-flowered mutation and the wild-type version of the gene, results in a third flower type that is intermediate in form -- being elongated and yellow -- but tubular and containing the reproductive structures of the interior florets.

The scientists identified the responsible gene and sequenced it to show that in the double-flowered mutation, the portion of the gene that functions as an on/off switch is disrupted so that the instructions for making the outer rays are turned on in the portions of the plant that would normally produce the internal disc florets. In the second mutation, which results in the tubular florets, the insertion of a "jumping gene" disrupts the ability of the plant to produce normal ray florets. As a result, tubular florets are produced in place of the normal ray florets.

Finally, the scientists screened hundreds of sunflower varieties -- wild type, double-flowered and tubular -- and found that wild-type sunflower varieties never have a mutation in the HaCYC2c gene, while the double-flowered varieties always have the same mutation in the on/off switch. In addition, the tubular varieties always have a disrupted copy of the gene.

"All of this evidence tells us that the mutation we've identified is the same one that van Gogh captured in the 1800s," Burke said.

Additional authors include former post-doctoral researchers Mark Chapman, Shunxue Tang and Dorthe Draeger, current post-doctoral researchers Savithri Nambeesan and Jessica Barb, undergraduate Honors student Hunter Shaffer and former UGA professor Steven Knapp.

The research was funded by the Gloeckner Foundation Floriculture Grants Program and the National Science Foundation.

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Story Source:

The above story is reprinted from materials provided by University of Georgia. The original article was written by Sam Fahmy.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

---

Journal Reference:

1. Mark A. Chapman, Shunxue Tang, D?rthe Draeger, Savithri Nambeesan, Hunter Shaffer, Jessica G. Barb, Steven J. Knapp, John M. Burke. Genetic Analysis of Floral Symmetry in Van Gogh's Sunflowers Reveals Independent Recruitment of CYCLOIDEA Genes in the Asteraceae. PLoS Genetics, 2012; 8 (3): e1002628 DOI: 10.1371/journal.pgen.1002628

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

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Now It's Jeff Bezos Diving Into Ocean Exploration

Installation of the Apollo 11 engines. Credit: NASA Marshall Space Flight Center

As the commercial space race has taken off over the last decade, we've gotten used to the idea of millionaires and billionaires building the spacecraft for the next generation of space travel and exploration. Now many of the same high-rollers are using their means to go after our own planet's next great frontier: the unexplored depths of the oceans.

But leave it to Jeff Bezos to do both space and the ocean at once.

Bezos, the Amazon.com billionaire and man behind the secretive space company Blue Origin, announced today that he intends to recover at least one of the Apollo 11 engines from the bottom of the sea. After those five engines blasted Neil Armstrong, Buzz Aldrin, and Michael Collins into space back in July 1969, they fell into the Atlantic Ocean and haven't been seen since. Today, Bezos reported on his blog that his team of undersea explorers had located the engines via "deep sea sonar," and that he plans to try to raise up at least one of them.

The Apollo announcement follows a wave of press about the ocean bottom, as filmmaker and explorer James Cameron just returned from a trip to the Mariana Trench in a one-man sub. Besides Bezos and Cameron, the new breed of celebrity explorers also includes Richard Branson of Virgin Atlantic. In addition to bankrolling Virgin Galactic, which would fly anyone willing to pay the steep ticket price to suborbital space, Branson is also working with seasoned submersible builders on his own deep ocean explorer called Virgin Oceanic.

Some have called this a "race to the bottom," but the growth of ocean exploration offers so much more than that. We're waiting to see what other projects these adventurers come up with.

Source: http://www.popularmechanics.com/how-to/blog/now-its-jeff-bezos-diving-into-ocean-exploration-7698345?src=rss

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Keeping the Spark in Long Distance Relationships - The Food ...

1) Use the long distance phone app, Pair. Read about it here.
2) Make plans to spend holidays together, especially the major ones.

3) Take lots of pictures when you are together.

4) Create two 12-month calendars with each month featuring your pictures. Share one with your mate.

5) Designate a day and time when you talk to each other without interruptions (cell phones, kids, television, etc.) - enjoy some qtt (quality talk time).

6) Stay in touch using social media ? my favorite.

7)?Take turns visiting each other. Try meeting halfway or somewhere new.?

8) Send care packages. Add something fun or unexpected in the box, like chocolate chip cookies.

9) Call. If no one is home, leave a charming message.

10) Write love letters and mail them.?

11) ?Record a video message and send it via email.

12) Meet on Skype for a show-and-tell.

13) When you do see each other, prepare a meal together and choose an intimate setting to enjoy it at such as a patio/balcony. Don't worry about the mess in the kitchen.

?

Do you have anything to add to this list?

The purpose of the meme is to get to know everyone who participates a little bit better every Thursday. Visiting fellow Thirteeners is encouraged! If you participate, leave the link to your Thirteen in others? comments. It?s easy, and fun!
Trackbacks, pings, comment links accepted!

View More Thursday Thirteen Participants

Source: http://thefoodtemptress.blogspot.com/2012/03/keeping-spark-in-long-distance.html

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Clocking galaxy clusters to gauge dark energy

The universe's oldest light and its largest objects could provide a new way to study dark energy, the mysterious entity believed to be pushing the universe apart at an ever-faster rate.

The discovery of the universe's accelerating expansion earned three physicists a Nobel prize last year, but no one knows its source. "What's causing the acceleration?" asks Rachel Bean of Cornell University in Ithaca, New York. "We really don't have a clue."

The leading explanation holds that there is a set amount of repulsive energy, represented by the cosmological constant, in every spot in space ? as the cosmos expands, more space is created, leading to ever-faster expansion. But other models suggest that dark energy may vary or that gravity itself behaves strangely over vast distances. Measuring dark energy's strength over time could provide some answers.

To do so, researchers need to determine the expansion rate of the universe at different cosmic eras by looking further into space. That's because light travels at a finite speed, so looking further away means looking back further in time. So far, astronomers have used techniques such as measuring the distances from Earth to supernovae.

Galaxy clusters

Now Nick Hand at the University of California, Berkeley, and colleagues are the first to use the motion of galaxy clusters to gauge cosmic expansion. Because gravity pulls objects together at known rates and dark energy pushes them apart, studying whether two neighbouring clusters fall together as expected sheds light on dark energy's strength.

First the researchers overlaid a map of 7500 galaxy clusters spotted by the Sloan Digital Sky Survey on top of a map of the universe's oldest light, called the cosmic microwave background radiation, made with the Atacama Cosmology Telescope (ACT) in Chile.

When photons of this ancient light, which permeates all of space, pass through a galaxy cluster, they get squashed or stretched depending on whether the cluster is moving towards or away from Earth, in the same way an ambulance siren sounds higher in pitch as it approaches and then lowers as it zooms past.

Next the team measured the difference in how squashed or stretched the light was in pairs of clusters, allowing them to gauge the clusters' relative motions along the line of sight to Earth.

Dark energy changes

There is not yet enough data to determine if dark energy changes in time, but the measurement shows the technique could test this in the future, says team member Arthur Kosowsky of the University of Pittsburgh in Pennsylvania. "This is the first step on a road to using velocities as a way to measure the development of structure in the universe," he says.

Team member David Spergel at Princeton University agrees. "We can't say anything profound about dark energy yet. But the fact that we now have this new tool means we're in a better position to do something interesting," he says.

Fortunately more information will be available soon. The ACT is getting a new detector in May, and the Sloan survey continues to spot more clusters. "In a year or two we'll be able to redo this analysis with much higher sensitivity," Spergel says. "That's all we need to do now: wait for the data to get better."

Journal reference: arxiv.org/abs/1203.4219

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Source: http://feeds.newscientist.com/c/749/f/10897/s/1de65630/l/0L0Snewscientist0N0Carticle0Cdn216380Eclocking0Egalaxy0Eclusters0Eto0Egauge0Edark0Eenergy0Bhtml0DDCMP0FOTC0Erss0Gnsref0Fonline0Enews/story01.htm

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Nigeria to raise pension fund stock market limit

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Source: http://news.yahoo.com/nigeria-raise-pension-fund-stock-market-limit-052649652.html

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Small Business Telephone Systems - A Case Study in Operational ...

Historically, UK small businesses have received a poor deal from the telecommunications industry, particularly hardware vendors. Expensive and funtionally-limited telephony systems, beyond the reach of SMEs have left many operating with a single landline and a mobile phone. The advent of hosted telephony applications has revolutionised call-handling for many small firms, offering them the same (and frequently richer) feature-set as fully-loaded PBX systems deployed by much larger organisations. This case study below provides an illustration of the benefits of using a hosted telephony service: XYZ Plumbing - A small business with clear telephony needs XYZ Plumbing is a sole trader, owned and operated by Jim Ravenscroft. Jim's partner, Simone is able to deal with some telephone enquiries, but with two school age children, this isn't always possible.

Understandably, Jim is often on the road but he must be accessible at all times to deal with urgent plumbing problems. He also needs to publish a contact number prominently in the Yellow Pages (print and online versions) since this is how he generates new business. However, using his mobile number presents a number of problems: * He doesn't wish to carry two mobile phones and he's reluctant to give his personal number to customers or publish it in telephone directories; * Jim is keen to expand his business and he believes that using a mobile number on his vehicle, advertisements and cards does not create the impression he'd like for the firm; * Unless he published his home telephone number and Simone was always available to take calls, Jim is only able to handle one call at a time. Consequently, he has lost customers to competitors. * Jim often receives calls to his mobile out of hours. Sometimes these are urgent but more often than not, callers in the evening are simply after a quotation for new central heating installations - something in which Jim specialises. He has no way of knowing until he answers the call and often he's obliged to spend too long dealing with new enquries at inappropriate times. Numberstore solved Jim's problems by providing a Freephone 0800 number which automatically and intelligently routes calls to his landline and mobile number according to the time of day. Using Numberstore's online control panel, Jim was quickly able to configure call management to suit his day to day needs. He set up an IVR menu with a professionally recorded voice prompt which operates on a Time of Day Routing Plan as follows: Monday to Friday: 9am-5pm * By forcing the CLI to present Jim's 0800 number, Jim knows that it is a business call and not a friend or relative, before he picks up (whether he receives it on his landline or his mobile). * All calls to Jim's 0800 number are answered instantly with a professional announcement: "Thank you for calling XYZ Plumbing. If your call is urgent, please press 1. For new central heating installations, press 2 and for all other enquiries, please press 3 or hold. Your call will be answered momentarily." * Pressing 1 routes to a "Hunt Group". This delivers calls simultaneously to Jim's mobile number and his landline. He can pick up whichever he's closest to at the time. Should he be unable to answer either, the caller is routed to a voice mailbox. Jim had a special prompt recorded for his urgent callers to assure them that they would receive a swift response. Any messages left for Jim are emailed to him instantly. He also receives an SMS message alerting him to the new voicemail. If Jim is by his computer he can play the audio file, if not, he can dial in to listen to the message. * Pressing 2 delivers calls only to Jim's landline (not his mobile number). If he's by the phone and able to take a call, he picks up. If not, the caller hears another custom message thanking for them enquiring about Jim's central heating installation service; asking them to leave a brief message and confirming that Jim will contact them shortly. Jim then receives an email with the voicemail message. The email displays the caller's number, making it easy for Jim to return the call, should the caller forget to leave their number. * Pressing 3 delivers calls to Simone's mobile number. If Simone is unable to answer, the caller is routed to a mailbox with a general greeting. * If the caller presses no button, calls are delivered as per option 3. Out of Hours * All calls to Jim's 0800 number are answered instantly, but the message is slightly different from the daytime prompt: "Thank you for calling XYZ Plumbing. If your call is of a general nature, please call back between 9am and 5pm Monday to Friday or press 1 to leave a message. If you require our services urgently, please press 2." * Pressing 2 delivers calls to a special Hunt Group in which Jim has included all possible destination numbers. His landline and mobile number and Simone's mobile are all called simultaneously. Because Jim has 24/7 access to Numberstore's online call management system, he is able to change the way his calls are answered easily and instantly (with no additional charges for doing so). His 0800 number and intelligent call management have proved invaluable for many other reasons: * Having an 0800 number allows Jim to move house, change his mobile service provider (and partner!) without changing the all-important contact number for XYZ Plumbing - which now appears in Yellow Pages for the next 12 months. He can update the destination numbers as frequently as he likes. * Jim chose a memorable number for his business which makes it easier for those who see his van passing on the motorway to remember Jim's number until they're able to call him. * Jim is "punching above his weight". Many plumbers appear in the Yellow Pages but not all offer Freephone 0800 numbers. Not only does this significantly increase the volume of new enquiries which Jim receives, it allows him to monitor the effectiveness of each Yellow Pages advertisement by analysing inbound call statistics. * Jim's business is growing quickly. He understands that he won't always be able to answer calls, but he also knows that he can continue to use his 0800 number even if he ends up sending calls to a forty-seat call centre. For further information, please visit Numberstore now. Numberstore is a division of Zimo Communications Limited, a UK digital communications company established with quality of service as its principal objective. For a large selection of 03 numbers, 0300 numbers, 0330 numbers, 0800 Numbers, 0845 numbers, 0871 numbers, 0808 numbers, 0844 Numbers, premium rate numbers and freephone numbers please click on the "numbers" link above.

Source: http://technology.ezinemark.com/small-business-telephone-systems-a-case-study-in-operational-efficiency-7d350fb2fc0f.html

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Setting Up An Internet Business Is Excellent However It Is Not ...

Thousands people today are turning to the Internet in order to try to earn some extra money in order to cover their bills. The trouble is people seem to believe that it is easy to start generating money online. The truth is that for the most part, it requires hard work and you will have to invest time in order to find success online.

You have to decide if being an online business owner is a good option for you. If you are one of those folks who feel you can merely set up a site and people will come and pay for your products, stop now. This is actually not the way it works. Don?t waste your time or money if you don?t suppose you can commit at least 2 to 4 hours a day to build your Internet business up.

Now, I realize that most of you already know that work is involved and you can?t simply set it and forget it like a pot roast. For you people congratulations this is a great choice. Below we will tackle a couple of things you will need to get going.

You will need to get a domain name and hosting for your domain so you can set up a site or blog. Although it is possible to generate money online without your own web site, it will be easier both starting off and in the long run. Letting people know who you are will be a major key in your internet business, and having your own blog or website will help you build name recognition.

When you have your own web site or blog, the next thing you will need is a way to earn money from it. Many people get started with Adsense as a way to make money from their web site. If you truly wish to earn a huge amount of money with Adsense, you will have to figure out how to get hundreds or thousands of people to your website each day. Of course, don?t forget about affiliate marketing, it should be one of the cornerstones of your online business. By utilizing affiliate marketing, you can actually pull in enough cash to replace your current income. Affiliate marketers can generate up to $200 for each sale they generate, and in many instances even more. Doesn?t that sound good? You can locate affiliate programs all over the Internet, merely execute a search in the search engines for "affiliate programs".

Now for the difficult part, you will need to get started building traffic to your website or blog. Site traffic is the key component to generating money on the Internet. When nobody looks at your web site or blog, there is nobody to click links or promote anything to. To generate site traffic, you can always utilize PPC. When you utilize pay per click methods, you have to put out money to get people to your site, whether they buy anything or not. In essence, you are paying whenever someone visits your site by clicking on one of your PPC adverts. And when you are a novice to Internet marketing, this can truly add up quickly if you don?t know what you?re doing.

You can always depend upon no-fee traffic exchange programs and systems. There are numerous free programs online that can help you generate traffic to your web site. It is quite easy to locate these traffic exchanges by just using the search engines and searching for no-fee traffic programs.

As long as you know that this is not a set and forget type of thing and that work is called for, earning the extra money that you need can be done by working online with your own Internet business.

In addition to Web Based Business, the author also regularly writes about antique wardrobe armoire and wardrobe trunks antique.

Source: http://internetbasedbusinessarticles.com/141926/setting-up-an-internet-business-is-excellent-however-it-is-not-necessarily-meant-for-everybody-and-i-will-explain-why/?utm_source=rss&utm_medium=rss&utm_campaign=setting-up-an-internet-business-is-excellent-however-it-is-not-necessarily-meant-for-everybody-and-i-will-explain-why

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Instagram Unveils A Sign-Up Page For Android Users, Still No Launch Date

Instagram has been iPhone-only for so long, and its executives have been so coy about their plans for other platforms, that it can be hard to believe the company will ever release an app for Android. And no, it still hasn't announced a launch date, but if you're an Android owner who wants the app, you should go to this page and sign up right now. Earlier this month, when TechCrunch's Alexia Tsotsis interviewed co-founder Kevin Systrom at South by Southwest, he teased the audience by waving around the Android app on-stage. Apparently it wasn't ready for a real demo, but he claimed that "in some ways, it's better than our iOS app."

Source: http://feedproxy.google.com/~r/Techcrunch/~3/S7neQGR-nIE/

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Most Anal Lesions Don't Cause Cancer in Men, Research Shows

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Source: http://news.yahoo.com/most-anal-lesions-dont-cause-cancer-men-research-130407521.html

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Home Improvements ? Important Factors to Keep in Mind | Culture ...

A craze which has grown in the past couple of years is DIY home improvement. One explanation is that individuals are trying to find options for cutting costs on their own, remodelling and other projects. Sometimes, it is vital to employ a contractor, although it can cost a lot of money. In this article, we?ll be looking at a few important factors to keep in mind if you?re planning to handle your own home improvement plans. Still, a good way to improve your home is to clean it thoroughly and regularly.

Safety is an important factor that should never be overlooked, when doing home repairs of any kind. Sometimes people who aren?t experienced at working with tools, and other kinds of equipment don?t take the required precautions. The eyes can be damaged easily with some of the tools and materials, so wear eye protection. When you work around construction, things are constantly flying at your eyes, therefore use precaution. When using loud power tools, it?s a good idea to wear hearing protection. A particle mask can save you from having difficulty in breathing, stemming from the poisonous substances, such as dirt, mold and insulation which you breathe in. House cleaners Melbourne can insure your home environment is healthy thanks to the green cleaning products they use.

Sometimes you are able to lower your costs upon materials and resources, when you get set up for a home restoration task. You never want to compromise on quality, but it may be possible to find the thing you need at a low price. Recycle centres or places such as Re-Stores have new materials for about half the price because those sold in your own home improvement or equipment stores. If you can find the things you need at these types of places, you can significantly reduce your costs, whilst still acquiring good quality materials. In regards to tools, you can often find used items which work well, either in the local community or online.

When it comes to cleaning after a huge home improvement project you might find yourself in huge trouble ? too much work to be done but you are already too exhausted, thus house cleaners Melbourne might prove really useful.

Source: http://culturepressreleases.com/important-home-improvement-tips/

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Advice to Follow for a Successful Home Improvement Project | Traffic ...

To help you get the results that you want, specifically in regard to your home improvement project, you need to be properly prepared. Uncountable problems may arise, especially for those that do not plan their home repairs in advance. The following is a quick overview of easy ways to do the right type of planning for your home improvement project ? let?s get started! wine aerator guides

One of the most important issues in regard to home renovations of any kind is the budget that you have to work with. Whether you?re doing the work yourself, or hiring a professional, it?s essential to know how much everything is going to cost. What you will need to purchase may include labor, supplies, and tools. It is usually a good idea to overestimate how much your project will cost because most of us lowball the cost as a general rule. If you?re hiring anyone, make sure you fully understand all of the costs that are going to be involved and look over the contract carefully. It is important to keep in constant contact with your contractor to make sure they are not going over the estimate they gave you. Looking at your home from the outside will give you a good idea of what you need to do to improve its overall curb appeal. The curb appeal of your home is very important. If you ever decide to sell your house, this is something that will aesthetically improve your chances of selling even if you are not ready now. The first impression that anyone has of your home will be looking at the front lawn. If it is in disrepair, you should clean it up or at least hire someone to do so. Cleaning up the front porch should be the next step of this process. Simply take the time to get it done. You may even want to consider replacing your front door if it?s looking the worst for wear. Even if you are going to make other home renovations, make sure the front of your house is exceptionally well kept. Vinturi wine aerator

Home inspectors are very useful individuals that can go through your house and help you decide on which home renovations need to be done right away. The inspector is a trained professional that will be able to spot small things that need to be done that you might miss. Many houses will have termites, a little pest that most people may not notice where as an inspector will. Inspectors will be able to show you which items need to be fixed and also help you avoid repairing things that can wait until later. These individuals are a fantastic investment that will save you money because of their experience and knowledge.

Planning is absolutely essential, especially when it comes to home improvement projects that need to be done right. Getting the job done is something that will be much easier, especially if you take the time to write out exactly what you want to do for your home improvement project. The best results possible can be achieved by planning in advance exactly what you need to do for your home improvement project today.

This entry was posted in Brain Injury Compensation and tagged home improvement projects, home improvement strategies, homne improvement planning by debra. Bookmark the permalink.

Source: http://www.valldelord.org/advice-to-follow-for-a-successful-home-improvement-project/?utm_source=rss&utm_medium=rss&utm_campaign=advice-to-follow-for-a-successful-home-improvement-project

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Present Relief May Want To A Specific Thing ... - Home Improvement

Posted March 22, 2012 By Willy in Kitchen Improvements With | Comments Off

Kitchen appliances are one of the biggest home expenses, and since many can last for several many years before requiring substitute, it is critical to choose the appropriate appliances for the kitchen to meet the requirements your family as well as the kind of your kitchen with Factory Outlet Coupon Codes because they have the greatest options for your hard-earned income.

Walk into their kitchen gadget store and you?ll find shelves of home equipment. The alternatives are usually mind-boggling. Rates vary based on brand names, and also as outlined by functions. It?s difficult to get a homeowner to find out which usually appliances for the kitchen work most effectively due to the fact all have good quality and overall worth. They will enable you to decide your requirements empower you to enjoy the best ways for your property and loved ones.

You?ll considerably happier with your acquire when it suits you better than an item you?re replacing. Think of the thing you need before you think about what you would like in order to increase the risk for brightest variety. Spend a little bit more to obtain the home appliance that may very best serve your requirements. A new kitchen appliance seem so great if its of proper high quality and they are of good working problem whether purchased at Factory Outlet Coupon Code at cheap pricing.

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When you shop for kitchen appliances, take all options and specific characteristics into consideration. Determine that it is something you would like and something you?ll need. More often than not, you can cut corners and cut costs without decreasing good quality criteria in Coupons simply because have only the top!

Related posts:

1. Searching For New Kitchen Appliances
2. The Purpose Of A Steamer Kitchen Appliance
3. Household Chores Made Simpler
4. Bathroom Vanities Are Like Craft At Present
5. Locating The Right Appliance Store For You

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Source: http://homeimprovement24.com/present-relief-may-want-to-a-specific-thing-not-be-successful/

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Doctors find clue in quest to predict heart attack

This undated handout images provided by Science Traditional Medicine/Scripps Translational Science Institute, shows on the left normal, healthy circulating endothelial cells (CEC). On the right are CECs from heart attack patients which appear abnormally large, misshapen and with multiple nuclei. Too often, people pass a cardiac checkup only to collapse with a heart attack days later. Now scientists have found a clue that one day may help doctors determine if a heart attack is imminent, in hopes of preventing it. (AP Photo/Scripps Translational Science Institute)

This undated handout images provided by Science Traditional Medicine/Scripps Translational Science Institute, shows on the left normal, healthy circulating endothelial cells (CEC). On the right are CECs from heart attack patients which appear abnormally large, misshapen and with multiple nuclei. Too often, people pass a cardiac checkup only to collapse with a heart attack days later. Now scientists have found a clue that one day may help doctors determine if a heart attack is imminent, in hopes of preventing it. (AP Photo/Scripps Translational Science Institute)

WASHINGTON (AP) ? Too often, people pass a cardiac checkup only to collapse with a heart attack days later. Now scientists have found a clue that one day may help doctors determine if a heart attack is imminent, in hopes of preventing it.

Most heart attacks happen when fatty deposits in an artery burst open, and a blood clot then forms to seal the break. If the clot is too big, it blocks off blood flow.

The problem: Today's best tests can't predict when that's about to happen.

"We don't have a way to get at whether an artery's going to crack, the precursor to a heart attack," said Dr. Eric Topol, director of California's Scripps Translational Science Institute.

Wednesday, Scripps researchers reported a new lead ? by searching people's blood for cells that appear to flake off the lining of a severely diseased artery.

Topol's team measured high levels of those cells, deformed ones, floating in the blood of 50 people who'd just had a heart attack. The research is reported in the journal Science Translational Medicine.

Next, Topol said his team soon will begin needed studies to learn how early those cells might appear before a heart attack, and if spotting them could allow use of clot-preventing drugs to ward off damage. Some San Diego emergency rooms will study an experimental blood test with chest-pain sufferers whose standard exams found no evidence of a heart attack, he said.

Don't expect a test to predict heart attacks any time soon ? a lot more research is needed, caution heart specialists not involved with the study. But they're intrigued.

"This study is pretty exciting," said Dr. Douglas Zipes of Indiana University and past president of the American College of Cardiology. It suggests those cells are harmed "not just in the minutes prior" to a heart attack, he said, "but probably hours, maybe even days" earlier.

"It's a neat, provocative first step," added Dr. William C. Little, cardiology chief at Wake Forest Baptist Medical Center. "But it is not a biomarker ready for prime time."

About 935,000 people in the U.S. have a heart attack every year, according to government figures. Doctors can tell who's at risk: People with high blood pressure and cholesterol, who smoke, have diabetes, are overweight or sedentary.

But there's no way to tell when a heart attack is imminent. Tests can spot that an artery is narrowing, or if a heart attack is under way or already has damaged the heart muscle. They can't tell if the plaque inside arteries is poised to rupture.

So it's not that uncommon for someone to suffer a heart attack shortly after passing a stress test or being told that their chest pain was nothing to worry about.

Wednesday's study, funded by the National Institutes of Health, investigated cells shed from the endothelium, or the lining of blood vessels, into the bloodstream. They're called "circulating endothelial cells."

First, Topol's team paired with Veridex LLC, a Johnson & Johnson unit that makes technology used to find cancer cells floating in blood. Could it find these cardiovascular cells, too?

The team took blood samples from 50 heart attack patients ? before they had any artery-disturbing tests or treatments ? and from 44 healthy volunteers. They counted lots of the endothelial cells floating in the heart attack victims' blood, and very little in the healthy people's blood.

The big surprise: The cells in the heart patients were grossly deformed. "Sick cells," is how Topol describes them.

The study couldn't tell when those abnormal cells first appeared ? and that's key, said Wake Forest's Little. It's not clear how many heart attacks happen too suddenly for any warning period.

But Topol theorizes there are plaques that break apart gradually and may shed these cells for up to two weeks before the heart attack. He cites autopsy studies that found people's arteries healed several plaque ruptures before the final one that killed them.

Topol said Scripps and Veridex have filed for a patent for a blood test to detect the abnormal cells.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-03-21-Heart%20Attack%20Clue/id-7f62a5a34cf54093b20453296809f892

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Efforts to save lives in Nigeria with clean cookstoves

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Source: http://news.yahoo.com/efforts-save-lives-nigeria-clean-cookstoves-203655603.html

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Windows Phone Inches Past Near-Dead Symbian In U.K. Market Share

Microsoft's Windows Phone platform seems to be picking up some steam across the pond, or so a new report from Kantar Worldpanel claims. According to their study, Symbian now only accounts for 2.4% of the UK smartphone market while the Windows Phone platform has grown from 0.5% last year to around 2.5%, barely inching ahead of Nokia?s former smartphone OS of choice. I know, a victory is a victory, but Windows Phone's triumph has much more to do with how far Symbian has fallen in just a year. As of February 2011, Symbian could be found on 12.4% of smartphones in the UK, with its popularity tanking over the intervening months.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/Yo7gm1047xQ/

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Nano-fat to fight cancer | ScienceBlog.com

For the past 40 years, radiation has been the most effective method for treating deadly brain tumors called glioblastomas. But, although the targeting technology has been refined, beams of radiation still must pass through healthy brain tissue to reach the tumor, and patients can only tolerate small amounts before developing serious side effects.

A group of researchers at The University of Texas Health Science Center at San Antonio have developed a way to deliver nanoparticle radiation directly to the brain tumor and keep it there. The method doses the tumor itself with much higher levels of radiation ? 20 to 30 times the current dose of radiation therapy to patients ? but spares a much greater area of brain tissue.

The study, published today in the journal Neuro-Oncology, has been successful enough in laboratory experiments that they?re preparing to start a clinical trial at the Cancer Therapy & Research Center, said Andrew Brenner, M.D., Ph.D., the study?s corresponding author and a neuro-oncologist at the CTRC who will lead the clinical trial.

?We saw that we could deliver much higher doses of radiation in animal models,? Dr. Brenner said. ?We were able to give it safely and we were able to completely eradicate tumors.?
The radiation comes in the form of an isotope called rhenium-186, which has a short half-life. Once placed inside the tumor, the rhenium emits radiation that only extends out a few millimeters.

But simply putting the rhenium into a brain tumor would not work well without a way to keep it there ? the tiny particles would be picked up by the bloodstream and carried away. That problem was solved by a team led by nuclear medicine physician William T. Phillips, M.D., and biochemist Beth A. Goins, Ph.D., in the Department of Radiology; and Ande Bao, Ph.D., a medical physicist and pharmaceutical chemist in the Department of Otolaryngology, all of the School of Medicine at the UT Health Science Center. They encapsulated the rhenium in miniscule fat molecules, or liposomes, about 100 nanometers across.

?The technology is unique,? Dr. Brenner said. ?Only we can load the liposomes to these very high radioactivity levels.?

The doctors hope to launch the clinical trial by summer.

Source: http://scienceblog.com/52845/nano-fat-to-fight-cancer/

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Titan's haze is dropping

Change in elevation of cloudy layer suggests seasonal cycles

Web edition : 9:23 am

THE WOODLANDS, Texas ? The sky is falling on Titan. An upper layer of the Saturnian moon?s hazy shroud has plunged more than 100 kilometers since the Cassini spacecraft whizzed by in 2004, suggesting that shifting seasons can do more than dump rain.

Early Cassini images revealed a smoggy world circled by a detached, hazy layer that hovered 500 kilometers above the moon?s surface. Now, new images reveal, that layer has sunk to an altitude of around 360 kilometers, said Robert West of the Jet Propulsion Laboratory in Pasadena, Calif., on March 19 at the 42nd Lunar and Planetary Science Conference.

The layer?s current altitude almost precisely matches the haze?s position in 1981, when the Voyager spacecraft recorded images of Titan hiding beneath the clouds. ?To me, that?s just astonishing,? said West.?

One year on Titan is the equivalent of nearly 30 years on Earth ? and now, one Titan year after Voyager, the moon looks more or less as it did in 1981. When Cassini first swung by in 2004, the haze had ballooned outward and covered the entire moon except for the wintry north pole vortex. Now, as winter comes to the south, the haze is shrinking, and images snapped by Cassini in late February reveal the beginnings of a vortex at the south pole.

?It?s really spectacular,? said planetary scientist John Spencer of the Southwest Research Institute in Boulder, Colo. ?You?re seeing this world changing before your eyes, and there are all these totally unexpected, very dramatic patterns that show up. You just can?t wait to see what?s going to happen next.?

Scientists suspect that shifting seasons are accompanied by changing atmospheric patterns, and the collapsing haze layer could be one of a constellation of seasonal cycles. But so far, researchers haven?t? been able to explain the mechanics of the falling haze.

?This is new; we?re seeing it for the first time with Cassini,? West says. ?We?ll see within the next couple of years how this evolves.?

Found in: Astronomy and Atom & Cosmos

Source: http://www.sciencenews.org/view/generic/id/339257/title/Titans_haze_is_dropping

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New Customer Service Training Available On Demand from Mastery ...

Written by admin on Monday, March 19th, 2012 ( Start discussion )
Tags: Available, Customer, Demand, from, Mastery, Service, Technologies, Training

Novi, MI (PRWEB) March 16, 2012

Mastery Technologies has expanded its catalog of workplace training to include business-skills content from the most respected brand in customer service training, Telephone Doctor. Seven of the first courses, now available in Masterys Video On Demand, focus on specific customer service skills imperative to service providers in any industry.

The importance of customer service is well known to most organizations and recently the media has drawn more attention to the need for careful hiring and training of customer service professionals. US News reports the customer service profession will see significant job growth in the next decade based on a Bureau of Labor Statistics projection that 338,400 customer service jobs will need to be filled by 2020. In addition to training customer service representatives on products and services, companies also need to provide basic skills training to ensure their corporate service standards are met.

I love how Nancy Friedmans coaching and the video dramatizations engage the learner, keeping them entertained while providing the skills needed to use these best practices on the job, says Bill Marker, President of Mastery Technologies.

Masterys robust course selection includes titles such as Business Friendly Customer Service and The Service Mentality that set the tone for an organizations service culture; a defined service point of view sets a higher standard for the organizations representatives. Additional skill-specific courses such as Essential Telephone Skills and Proactive Customer Service impart the needed knowledge and tools for customer service representatives to uphold the service culture.

Each course includes rich video content, a leader guide for the organizations trainer, a participant guide for the employee, and an interactive quiz to confirm the learners acquisition of knowledge and reinforce the concepts they should apply on the job. All seven of these titles are now available online on any of Masterys web sites:

The Service Mentality: 7 Characteristics of Excellent Service Providers
Five Forbidden Phrases (3.0)
Six Cardinal Rules of Customer Service (3.0)
Proactive Customer Service (3.0)
Essential Telephone Skills: 10 Core Skills to Delivering Excellent Service Over the Phone
Business Friendly Customer Service
Influencing The Interaction: 6 Practices for a More Satisfying Customer Experience

About Mastery Technologies Inc.

Mastery Technologies, founded in 1974, has partnered with leading video content providers to co-produce the largest interactive multimedia training library available to the workplace health, safety and environmental marketplace. Today, Mastery is extending their model to encompass all areas of workplace training. Mastery has helped thousands of companies develop greater competency and have created safer and secure workplaces. By expanding the scope of training Mastery believes it can enhance customer benefits, and help build more successful and effective organizations. Masterys ultimate vision is to help reach every working individual with quality training.

Source: http://www.cheshireportablebuildings.com/?p=63

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Who Needs a Social Media Agency? - Build A Better Business Online

Written By: Michael Gillen?on?March 17, 2012 No Comment

Do you want to dive into the wonderful world of online marketing? Do you think you need a professional social media agency (or, even a general marketing firm) in order to do well at it? Well, while I think that it?s always a solid idea to do so (hey, I do work for one), there are times when you don?t have the funds to do so. So, what should you do if you really have to do it on your own? There are a number of things that you can do by yourself in order to get yourself a bit further.

Like I said, I work for a social media agency. So I would like to hope that I know what I?m talking about with respect to social media management. While I don?t have the time right here to go into as much detail as I feel this area needs, I feel that I can go over it in broad strokes so that you at least know where to get setup.

The first thing you need to do is to if you want to master social media is to post habitually. I generally feel that once a day is a good rule of thumb, and if you have any reason to do more frequently you should try to combine posts. If somebody lands on your Facebook page and sees that you haven?t made any posts in a while then chances are that they will think that you have forgotten your page, and you certainly don?t want that!

Next, you need to remember that you need to give value with each and every post that you make, otherwise people are significantly less likely to ever interact with you, let alone give your posts the time of day. Deals, coupons, new products, polls, contests, or even funny tidbits and links to related articles are all lovelyways that you can give your readers something that will make them want to come back to your Facebook page again and again.

To finish, have fun. Social media is a new and vibrant field, so you should ensure that you enjoy it. If you treat it as just another project, your readers will notice and they?ll pass on you. But if you like what you?re writing, your readers will without any doubt like what they?re reading.

fishbat is a web marketing firm that can help you with your online reputation management. Check out fishbat.com today for more information!

Tags: Internet marketing

Source: http://articles.buildabetterbusinessonline.com/who-needs-a-social-media-agency-things-you-can-do-on-your-own/

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EVL-BP 2012 : Fifth International Workshop on Evolutionary ...

Please apologise if you receive multiple copies.

------------------------------------------------

-------------------------------
C A L L F O R P A P E R S
-------------------------------

Fifth International Workshop on

Evolutionary Business Processes (EVL-BP 2012)

in conjunction with the

16th IEEE International EDOC Conference

September 10 - 14, 2012, Beijing, China

http://www.leduotang.com/evl-bp

Submission deadline: 1st April 2012

Scope
-----

Enterprises face the challenge of rapidly adapting to dynamic business environments. The traditional
approach to process management is only partially appropriate to this new context, and calls
for the advent of new, evolutionary business processes. This new approach attempts to address
specific issues related to flexibility and adaptation such as design of easily adaptable processes,
dynamic handling of unexpected situations, optimality of adaptations, and change management.
Central to the field of evolutionary business processes is the notion of requirement, which drive the
change of business processes through their life-cycles.

The evolution of processes and their underlying software systems becomes more and more an
important and interesting topic in business process management. Since the life time of software
systems frequently spans many years, business processes modelled on top of systems cannot be
assumed to remain fixed, and migration between different versions is essential. As a consequence,
modelling and management techniques developed in the context of ad-hoc, short-term composition
of services and their processes lack the necessary constructs to concisely express the gradual
evolution of processes and software systems and new dynamic and/or declarative approaches in
this context are required.

The evolutionary approach to business processes raises a number of challenges: extracting
declarative specifications from domain experts, expressing these declarative specifications in an
appropriate language or formalism, as well as designing, monitoring, checking compliance or
dynamically adapting business processes according to a set of requirements, identification and
handling of changes, management of process versions. Evolution in business processes takes place
in a wide number of domains, and is expected to impact existing and future technology choices,
business practices and standardization efforts.

This workshop will be an opportunity for participants to exchange opinions, advance ideas, and
discuss preliminary results on current topics related to dynamic and declarative business processes.
A particular interest will be taken in bridging theoretical research and practical issues. To this end,
contributions stating open problems, case studies, tool presentations, or any other work assessing
the practical significance of dynamic and declarative business processes by means of concrete
examples and situations, will be particularly welcome. Work in progress, position papers stating
broad avenues of research, and work on formal foundations of dynamic and declarative business
processes are also sought-after.

Topics
------

* Topics of the workshop include but are not limited to:
* Evolutionary business process modelling
* Dynamic business process specification
* Implementation issues for evolutionary processes
* Tools for evolutionary processes
* Methodologies for evolutionary processes
* Real-world use cases of evolutionary business processes
* Business rules and policies
* Rule driven business process engines
* Business + technical requirements for evolutionary processes
* Mathematical foundations of evolutionary business processes
* Formal models of dynamic business processes
* Monitoring of dynamic business processes
* Validation and model checking of dynamic business processes
* Software engineering methods, languages, and standards for dynamic business processes
* Service-oriented architectures and dynamic business processes
* Interoperability for dynamic business processes
* Semantic Web and ontologies and evolutionary business processes
* Collaboration and evolutionary business processes
* Data-driven process evolution
* Evolution of cross-organisational processes / process choreographies
* Complex event processing models/support for dynamic business processes

Submission
----------

The workshop duration is a whole day. It will comprise presentations of accepted papers, tool
presentations, and one keynote. All submissions will be peer reviewed by at least three members
of the program committee. Submissions should be 8 pages long and must use the two-column
format of IEEE conference proceedings and include the author?s name, affiliation, and contact
details. Papers must be submitted as PDF files using EasyChair.

Authors will be notified about the decision by the program committee. At least one author of
each accepted paper must participate in the workshop. The papers accepted for the EDOC 2012
Workshops will be published with their own ISBN in the IEEE Digital Library (pending approval
by IEEE), which is accessible by IEEE Xplore. At least one of the authors for each accepted paper
should register for the main conference in order to present their papers.

Important Dates
---------------

Paper Submission: March 1, 2012
Paper Notification: May 28, 2012
Camera Ready Copy Due: June 15, 2012
Workshop: September 10-11, 2012

Workshop Co-chairs
------------------

Dragan Gasevic, Athabasca University and Simon Fraser University, Canada
Georg Grossmann, University of South Australia
Sylvain Halle, Universite du Quebec a Chicoutimi, Canada
Florian Rosenberg, IBM T.J. Watson Research Center, USA

Program Committee
-----------------
Colin Atkinson, Universitaet Mannheim, Germany
Ebrahim Bagheri, Athabasca University, Canada
Claudio Bartolini, HP Labs Palo Alto, USA
Andrew Berry, Deontik, Australia
Domenico Bianculli, University of Lugano, Switzerland
Marko Boskovic, Research Studios Austria, Austria
Antonio Bucchiarone, Fondazione Bruno Kessler, Italy
Christoph Bussler, Xtime, Inc, USA
Marlon Dumas, University of Tartu, Estonia
Luciano Garcia-Ba?nuelos, Universidad Autonoma de Tlaxcala, Mexico
Guido Governatori, University of Queensland, Australia
Reiko Heckel, University of Leicester, UK
Gerti Kappel, Vienna University of Technology, Austria
Rania Khalaf, IBM Watson Research Center, USA
Marcello La Rosa, Queensland University of Technology, Australia
Florian Lautenbacher, Senacor Technologies, Germany
Philipp Leitner, Vienna University of Technology, Austria
Niels Lohmann, Universitaet Rostock, Germany
Wolfgang Mayer, University of South Australia, Australia
Anton Michlmayr, Vienna University of Technology, Austria
Zoran Milosevic, Deontik, Australia
Hamid Reza Motahari Nezhad, HP Labs, USA
Shin Nakajima, National Institute of Informatics, Japan
Leo Obrst, The MITRE Corporation, USA
Cesare Pautasso, University of Lugano, Switzerland
Maja Pesic, Technical University of Eindhoven, The Netherlands
Manfred Reichert, University of Ulm, The Netherlands
Stefanie Rinderle-Ma, University of Vienna, Austria
Shazia Sadiq, The University of Queensland, Australia
Vladimir Tosic, NICTA, Australia
Simon Tragatschnig, University of Vienna, Austria
Franck Van Breugel, York University, Canada
Manuel Wimmer, Vienna University of Technology, Austria

Source: http://www.wikicfp.com/cfp/servlet/event.showcfp?eventid=22455©ownerid=21350

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